Benfotiamine CAS NO.22457-89-2

Benfotiamine Basic information
Product Name:	Benfotiamine
Synonyms:	benzoylthiamineo-monophosphate;berdi;bietamine;biotamin;btmp;betivina;neurostop;nitanevril
CAS:	22457-89-2
MF:	C19H23N4O6PS
MW:	466.45
EINECS:	245-013-4
Product Categories:	Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals; Phosphorylating and Phosphitylating Agents;Sulfur & Selenium Compounds; Pharmaceutical intermediate;BIOTAMIN;API

Test Item	Analysis Specification	Result
Description	White to almost white crystal	White to almost white crystal
Identification	A: IR spectra shows the similarity between sample and standard B: The retention time of the major peak corresponds with it of the reference standard	Complies Complies
Solution color and clearness	Colorless to pale-yellow clear solution	Complies
Chlorides	Not more than 0.053%	<0.053%
Sulphate	Not more than 0.011%	<0.011%
Loss on drying	Not more than 1.5%	0.66%
Heavy metals	Not more than 0.002%	<0.002%
Related Substances	TMP :Not more than 0.15% Benzoic acid :not more than0.1% Amide: not more than 0.40% Single unknown impurity: not more than0.1% Thiamine: not more than0.1% Total impurities: Not more than 1.5%	<0.025% No detectable 0.06% 0.08% No detectable 0.33%
Residual solvents	Dichloromethane: not more than 600ppm Isopropanol: not more than300ppm	No detectable 64ppm
Microbial limits	Total bacteria: not more than100cfu/g Yeast and mould: not more than50cfu/g Escherichia coli: no detectable	<10 cfu/g <10 cfu/g No detectable
Assay(Dry Basis)	98.0%~102.0%	99.2%
Conclusion	Complies with company Standard.