2-[(5-Bromo-2-methylphenyl)methyl]-5-(4-fluorophenyl)thiophene CAS NO.1030825-20-7

Name	2-[(5-Bromo-2-methylphenyl)methyl]-5-(4-fluorophenyl)thiophene
Other name	2-(5-Bromo-2-methylbenzyl)-5-(4-fluorophenyl)thiophene;Thiophene, 2-[(5-bromo-2-methylphenyl)methyl]-5-(4-fluorophenyl)-;Canagliflozin intermediate
CAS	1030825-20-7
Molecular formula	C18H14BrFS
Molecular weight	361.27
Appearance	White powder
Purity	98%min.
Application	Kaglenet intermediate

Item	Standard	Test Results
Identification	A.H-NMR:Comply with the structure	Complies
	B.LC-MS:Comply with the structure	Complies
	C.The IR spectrum of sample should be identical with that of reference standard;	Complies
	D.HPLC-ESI-MS The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay.	Complies
Crystallinity	meets the requirements.	Complies
Loss on drying	≤2.0%	0.19%
Heavy metals	≤10 ppm	<10ppm
Water	≤1.0%	0.1%
Sulphated ash	≤0.5%, determined on 1.0 g.	0.009%
Related substances	Unspecified impurities: for each impurity ≤0.10%	<0.10%
Related substances	Total Impurity ≤0.5%	0.18%
Purity	≥99.0%	99.7%
Assay	99.0%~101.0% (anhydrous substance).	99.8%
Storage	Preserve in well-closed, light-resistant and airtight containers.	Complies