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Thiamphenicol CAS NO.15318-45-3
- FOB Price: USD: 1.00-1.00 /Kilogram Get Latest Price
- Min.Order: 10 Kilogram
- Payment Terms: L/C,D/A,D/P,T/T
- Available Specifications:
99%(10-500)Kilogram
- Product Details
Keywords
- 15318-45-3
- Methylsulfonyl chloramphenicol
- thiophenicol
Quick Details
- ProName: Thiamphenicol
- CasNo: 15318-45-3
- Molecular Formula: C12H14Cl2N2O7S
- Appearance: white or yellowish-white crystalline p...
- Application: Antibacterial. D -form as antimicrobia...
- DeliveryTime: prompt shipment
- PackAge: 25kg drum
- Port: Shanghai,China
- ProductionCapacity: 2000 Metric Ton/Year
- Purity: 99%min
- Storage: sealed and stored in cool places.
- Transportation: by sea,air
- LimitNum: 10 Kilogram
- Related Substances: ≤0.2%
- Residue on Ignition: 0.1%
- Heavy Metal: ≤10ppm
- Valid Period: 2 years
- EINECS No: 239-355-3
Superiority
Introduction
Product Name: Thiamphenicol
CAS: 15318-45-3
MF: C12H15Cl2NO5S
MW: 356.22
EINECS: 239-355-3
Details
|
Item |
Specifications |
Results |
|
Appearance |
Fine white or yellowish-white crystalline powder or crystals |
Fine white crystalline powder |
|
Identification |
According to BP2012 |
Complies |
|
Light absorption |
According to BP2012 |
Complies |
|
Acidity or alkalinity |
According to BP2012 |
Complies |
|
m.p |
163~167℃ |
165℃ |
|
Specific optical rotation |
-21°~-24° |
-22° |
|
Chloride |
≤200ppm |
<200ppm |
|
Sulphated ash |
≤0.1% |
0.05% |
|
Heavy metals |
≤10ppm |
<10ppm |
|
Loss on drying |
≤1.0% |
0.02% |
|
Assay |
98.0%~100.5% |
99.9% |
Application
Thiamphenicol (also known as thiophenicol and dextrosulphenidol) is an antibiotic. It is the methyl-sulfonyl analogue of chloramphenicol and has a similar spectrum of activity, but is 2.5 to 5 times as potent. Like chloramphenicol, it is insoluble in water, but highly soluble in lipids. It is used in many countries as a veterinary antibiotic, but is available in China and Italy for use in humans. Its main advantage over chloramphenicol is that it has never been associated with aplastic anaemia.
Thiamphenicol is also widely used in Brazil, particularly for the treatment of sexually transmitted infections and pelvic inflammatory disease.
Unlike chloramphenicol, thiamphenicol is is not readily metabolized in cattle, poultry, sheep, or humans, but is predominantly excreted unchanged. In pigs and rats the drug is excreted both as parent drug and as thiamphenicol glucuronate.