N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitro-4-quina CAS:162012-67-1 CAS NO.162012-67-1

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Name of product:	4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro-
Purity:	99.0%min	CAS:	162012-67-1
MF:	C14H7ClF2N4O2	MW:	336.69
Category	Afatinib Intermediates
Synonyms:	4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro-;N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine;4-(3-chloro-4-fiuoro-phen...;4-(3-chloro-4-fiuoro-phenylaMino)-7-fluoro-6-nitroquninazoline;N-(3-chloro-4-fluorophenyl)-N-(7-fluoro-6-nitroquinazolin-4-yl)acetaMide;(3-Chloro-4-fluorophenyl)(7-fluoro-6-nitroquinazolin-4-yl)amine;N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitro-4-quinazolinamine;Afatinib intermediate A
Appearance:	yellow powder

Items	Standard	Analysis data
Appearance	yellow to brown solid	yellow solid
Purity (HPLC Area Normalization)	≥98.0%	99.21%
Content (HPLC external standard method)	≥97.0%	97.87%
Water (Carie Fischer method)	≤0.5%	0.18%
Ignition residue	≤0.5%	0.26%
Loss on drying	≤0.5%	0.11%
Related substance-3-chloro-4-fluoro-phenylamine	≤0.5%	0.09%
Related substance-7-fluoro-6-nitro-4-(H)-Quinazoline	≤1.0%	0.03%