China (Mainland)
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ChinaZoledronic Acid powder 99% factory 118072-93-8 CAS NO.118072-93-8
- FOB Price: USD: 1.00-1.00 /Gram Get Latest Price
- Min.Order: 100 Gram
- Payment Terms: L/C,D/P,T/T,Other
- Available Specifications:
99%(100-500)Gram
- Product Details
Keywords
- 118072-93-8
- ZOLEDRONATE
- Zoledronic Acid
Quick Details
- ProName: ChinaZoledronic Acid powder 99% factor...
- CasNo: 118072-93-8
- Molecular Formula: C5H10O7N2P2 ?H2O
- Appearance: White crystalline powder
- Application: Metabolism Drug; Carcino-Chemotherapeu...
- DeliveryTime: prompt shipment
- PackAge: on request
- Port: Zhengzhou
- ProductionCapacity: 10 Metric Ton/Year
- Purity: 99%min
- Storage: Stored in cool and ventilated warehous...
- Transportation: BY SEA,AIR
- LimitNum: 100 Gram
- Related Substances: not avaliable
- Residue on Ignition: not avaliable
- Heavy Metal: 10ppm
- Valid Period: 2 years
- CAS No.: 118072-93-8
Superiority
| Synonym: | Zoledronate |
| Application: | A protein kinase C activator with apoptotic effects |
| CAS Number: | 118072-93-8 |
| Purity: | ≥99% |
| Molecular Weight: | 272.09 |
| Molecular Formula: | C5H10N2O7P2 |
Description
Zoledronic acid, one of the most potent nitrogen-containing bisphosphonates, induces anti-proliferative and apoptotic effects on multiple myeloma cell lines in vitro by activating protein kinase C. Zoledronic acid also inhibits proliferation of human foetal osteoblastic cell line (hFOB) with an IC50 of 40 μM. In cultures of freshly isolated rabbit and human osteoclasts zoledronic acid (10-100 μM) induced morphological features similar to apoptosis and Osteoclastogenesis was inhibited with an IC50 of 15 nM.
Details
|
Identification test Item |
Identification test standard |
Test Results |
|
Appearance |
White crystalline powder |
Complies |
|
Melting Point |
239°C |
Complies |
|
Heavy metals |
≤10PPM |
Complies |
|
Limit of Phosphite |
≤ 0.2% |
0.08% |
|
Total impurity |
≤ 0.5% |
0.13% |
|
Single impurity |
≤ 0.1% |
0.04% |
|
Water Content % |
5.5~6.5% |
5.6% |
|
Assay( Dried) |
≥98.0% |
99.0% |