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Tazarotene CAS NO.118292-40-3
- FOB Price: USD: 1.00-1.00 /Metric Ton Get Latest Price
- Min.Order: 1 Kilogram
- Payment Terms: L/C,D/A,D/P,T/T,
- Available Specifications:
99%(1-2)Metric Ton
- Product Details
Keywords
- 118292-40-3
- Tazorac
- Ethyl 6-((4,4-dimethylthiochroman-6-yl)ethynyl)nicotinate
Quick Details
- ProName: Tazarotene
- CasNo: 118292-40-3
- Molecular Formula: C21H21NO2S
- Appearance: crystalline powder
- Application: Skin Treatment Drug; Drug Acting on Sk...
- DeliveryTime: prompt shipment
- PackAge: 25kg drum
- Port: Shanghai,China
- ProductionCapacity: 2000 Metric Ton/Year
- Purity: 99%min
- Storage: Stored in dry and cool place, keeping ...
- Transportation: by sea,air
- LimitNum: 1 Kilogram
- Related Substances: 0.25%
- Residue on Ignition: 0.5%
- Heavy Metal: ≤20ppm
- Valid Period: 2 years
- CAS No.: 118292-40-3
Superiority
Function
Tazarotene is an acetylenic retinoid prodrug converted to the active metabolite, Tazarotenic acid, with selective affinity for retinoic acid receptors RARβ and RARγ. Tazarotene also upregulates TIGs (Tazarotene-induced genes), including the cell adhesion molecule TIG1 and the tumor-suppressor TIG3.
Application
Pharmaceutical raw materials
Tazarotene is third class DaiWei formic acid skin drugs, topical retinoids of precursor drugs for skin, regulate skin cell differentiation and proliferation, and so on, mainly is suitable for the treatment of plaque type psoriasis.
Details
Specification
|
ITEMS |
SPECIFICATION |
RESULTS |
|
|
BP2010 /EP6 |
Appearance |
crystalline powder |
Conforms |
|
Melting point |
About 205°C |
206.4°C~206.7°C |
|
|
Identification |
Meet the requirements |
Conforms |
|
|
Appearance of solution |
Clear, not more intense than Y7 |
Conforms |
|
|
PH |
2.4~3.0 |
2.60 |
|
|
Loss on drying |
≤0.5% |
0.04% |
|
|
Sulphated ash |
≤0.1% |
0.01% |
|
|
Heavy metals |
≤20 ppm |
<20 ppm |
|
|
Related substances |
≤0.25% |
Conforms |
|
|
Assay |
99.0%~101.0% |
99.8% |
|
|
USP32 |
Identification |
Meet the requirements |
Conforms |
|
Loss on drying |
≤0.5% |
0.04% |
|
|
Residue on ignition |
≤0.1% |
0.01% |
|
|
Heavy metals |
≤0.003% |
<0.003% |
|
|
Residue solvent - Ethanol |
≤0.5% |
<0.04% |
|
|
Chloride |
16.9%~17.6% |
17.1% |
|
|
Assay |
98.0%~102.0% |
100.0% |
|
|
Conclusion: The product complies with BP2010/USP32/EP6 standard |
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