Alvimopan CAS: 156053-89-3 CAS NO.156053-89-3

Items

Specifications

Results

Appearance

 White to almost white crystalline powder

white crystalline powder

Solubility

This product is soluble in DMF, methanol, ethanol, water and 0.1mol/L hydrochloric acid solution almost not.

108.4-108.5°C

Identification

UV

Has an absorption maximum at 230nm

Conforms

IR

Corresponding to reference spectrum

Conforms

HPLC

Should the retention time of the main peak of the reference solution

Conforms

Examination

Chloride

≤0.01%

Conforms

Related substances

Single impurity

≤0.5%

0.049%

Total impurity

≤0.1%

0.06%

Impurities I

≤0.1%

Not detected

Impurities II

≤0.1%

Not detected

Residual solvent

N-hexane

≤0.029%

0.0002%

Ethanol

≤0.5%

0.1%

Dichloromethane

≤0.06%

Not detected

Ethyl acetate

≤0.5%

Not detected

Tetrahydrofuran

≤0.072%

Not detected

Toluene

≤0.089%

Not detected

Chloroform

≤0.006%

0.001%

Loss on drying

≤0.5%

0.002%

Residue on ignition

≤0.1%

0.06%

Heavy metal

≤20ppm

Conforms

Assay

≥99.0%

99.52%

Conclusion:

Qualified