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Home > Products >  Aprepitant

Aprepitant CAS NO.170729-80-3

  • FOB Price: USD: 1.00-2.00 /Metric Ton Get Latest Price
  • Min.Order: 1 Metric Ton
  • Payment Terms: L/C,T/T
  • Available Specifications:

    99%(1-5)Metric Ton99%(5-20)Metric Ton

  • Product Details

Keywords

  • 170729-80-3
  • Aprepitant
  • 5-{[(2R,3S)-2-{(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy}-3-(4-fluorophenyl)morpholin-4-yl]methyl}-1,2-dihydro-3H-1,2,4-triazol-3-one

Quick Details

  • ProName: Aprepitant
  • CasNo: 170729-80-3
  • Molecular Formula: C23H21F7N4O3
  • Appearance: White powder
  • Application: Central Nervous System Drug; Anti-Emet...
  • DeliveryTime: Within 2 weeks after order confirmati...
  • PackAge: drum
  • Port: Qingdao Port
  • ProductionCapacity: 1000 Metric Ton/Year
  • Purity: 99%min
  • Storage: Store in cool and dry place, away from...
  • Transportation: By sea or by air
  • LimitNum: 1 Metric Ton
  • CAS: 170729-80-3

Superiority

 

Name
Aprepitant
CAS No 170729-80-3
MF C23H21F7N4O3
Purity 99%
Appearance white  powder

 

Details

Item

Specification

Test Results

Description

Off-white to light yellow powder  

Conforms

Identification  IR

HPLC, IR

Conform

Specific optical rotation

+68.0° ±3° (c=1.0, in Methanol)

67.49°

Melting point  

248±5 °C

248 -250°C

Water

≤0.5%

0.29%

Heavy metals  

≤10ppm  

Conforms

Residue on ignition  

Not more than 0.1% 

0.07%

Related substances

Desfluoro aprepitant NMT 0.15%

R,R,R-Diastereomer: NMT 0.15%

Any other individual impurity: NMT 0.10%

Total impurities: NMT 0.50%

0.09%

0.08%

0.06%

0.29%

Enantiomer purity  

NMT 0.15% of the S,R,S-enantiomer

0.07%

Assay (HPLC)

NLT 98.0% and NMT 102.0% (on the

anhydrous basis)

99.9%

Organic volatile impurities

Methanol NMT 2500 ppm; Xylene NMT

2170 ppm; Toluene NMT 890 ppm; DMSO

NMT 5000ppm

Conforms

Conclusion: Conforms to Authorized USP Pending Monograph

 

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