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Mesna 19767-45-4 CAS NO.19767-45-4
- FOB Price: USD: 1.00-1.00 /Kilogram Get Latest Price
- Min.Order: 1 Kilogram
- Payment Terms: L/C,D/A,D/P,T/T,
- Available Specifications:
99%(1-100)Kilogram
- Product Details
Keywords
- 19767-45-4
- sodium 2-mercaptoethanesulfonate
- Mesna
Quick Details
- ProName: Mesna 19767-45-4
- CasNo: 19767-45-4
- Molecular Formula: C2H6NaO3S2
- Appearance: White to off-white powder
- Application: pharmaceutical, Oncology drug
- DeliveryTime: one week
- PackAge: 25kg/drum
- Port: Shanghai
- ProductionCapacity: 1500 Metric Ton/Year
- Purity: 99%min
- Storage: Protect from humidity; keep in a dry, ...
- Transportation: by sea,air
- LimitNum: 1 Kilogram
- Related Substances: 0.1%
- Residue on Ignition: 0.2%
- Heavy Metal: 10ppm
- Valid Period: 2years
- EINECS: 243-285-9
Superiority
Mesna is an organosulfur compound. It is used in cancer chemotherapy involving cyclophosphamide and ifosfamide as an adjuvant. It is an acronym for 2-Mercaptoethane sulfonate Na (Na being the symbol for sodium). Mesna is used therapeutically to reduce the incidence of haemorrhagic cystitis and haematuria when a patient receives ifosfamide or cyclophosphamide for cancer chemotherapy. These two anticancer agents, in vivo, may be converted to urotoxic metabolites such as acrolein. It assists to detoxify these metabolites by reaction of its sulfhydryl group with the vinyl group. It also increases urinary excretion of cysteine
Details
|
Item |
Specification |
|
Specific rotation |
+39.5 to +41.5° |
|
State of solution(transmittance) |
Clear 98.0% min. |
|
Chloride[cl] |
0.020% max. |
|
Ammonium [NH4] |
0.02% max. |
|
Sulfate[SO4] |
0.020% max |
|
Iron[Fe] |
10ppm max. |
|
Heavy metals [Pb] |
10ppm max |
|
Arsenic[As2O3] |
1ppm max |
|
Other amino acids |
Chromatographically not detectable |
|
Loss on drying |
0.20% max. |
|
Residue on ignition[sulfated] |
0.10% max. |
|
Assay |
99.0% min |