5-Fluorouracil CAS NO.51-21-8

Appearance

White Powder

White Powder

Identification

The IR absorption spectrum conform

the reference spectrum

Complies

Appearance of

solution

Clarity  Clear

Absorbance ≤ 0.15 (440nm)                                  

≤ 0.10 (650nm)

Clear

0.033

0.009

Reducing

substances

(4mg/ml HCl

solution)

The solution turns blue or violet-brown

after addition of Starch solution &

0.01M iodine

The solution turns

violet-brown

Related

substances

(HPLC)

Impurity  B                   ≤0.2%

Impurity D                   ≤0.1%

Impurity G                   ≤0.1%

Impurity H                   ≤0.3%

Any other impurity       ≤0.05%

Total impurity               ≤1.0%

Nf

Nf

0.01%

Nf

0.03%

0.07%