Vincristine 57-22-7 CAS NO.57-22-7

This product is mainly used for clinical treatment of acute lymphoblastic leukemia, Hodgkin's disease, malignant lymphoma, small cell lung cancer, breast cancer, ovarian cancer, gastrointestinal cancer, and so on. Pharmacology: By affecting the formation of spindle cells, this production can stop the cells in mid-mitosis, and delay M cell cycle . There is also the inhibition of purine, RNA and DNA synthesis

A white or almost white crystalline powder; odourless; hydroscopic; darkens gradually on exposure to light or heat.

Action and indications: Vincristine sulfate is an alkaloid extracted from Vinca rosea. As a cell cycle specific drug, it can inhibit growth of neoplasm and formation of proliferating cell spindle, as a result, mitosis is stopped at its metaphase .

Clinically, it is similar to vinblastine sulfate with better effects, however, no cross tolerance is found between the two drugs. It has better effect in the treatment of various acute leukemia,especially acute lymphoblastic leukemia. 

In addition, it has some effect for malignant lymphoma , chorioepithelioma, breast carcinoma, neuroblastoma, nephroblastoma, brain tumour, lung cancer , leiomyosarcoma, cervix cancer and alimentary tract tumor.