Quinapril CAS NO.85441-61-8

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Min.Order: 5 Kilogram
Payment Terms: L/C,T/T,
Available Specifications:
99%(1-10)Metric Ton1/Metric Ton1USD

Product Details

Keywords

85441-61-8
QUINAPRIL HCL
ACCUPRIN

Quick Details

ProName: Quinapril
CasNo: 85441-61-8
Molecular Formula: C25H30N2O5
Appearance: POWDER
Application: Cardiovascular Drug; Antihypertensive
DeliveryTime: 10days
PackAge: 25kg carton drum
Port: SHANGHAI
ProductionCapacity: 10000 Metric Ton/Year
Purity: 99%min
Storage: Keep in cool and dry place. Keep away ...
Transportation: by sea
LimitNum: 5 Kilogram
Related Substances: 0.1%
Residue on Ignition: 0.1%
Heavy Metal: 10ppm
Valid Period: 2years

Superiority

Quinapril is an angiotensin-converting enzyme inhibitor (ACE inhibitor) used in the treatment of hypertension and congestive heart failure. A prodrug, it is converted to its active metabolite, quinaprilat, in the liver.

Quinapril inhibits angiotensin converting enzyme, an enzyme which catalyses the formation of angiotensin II from its precursor,angiotensin I. Angiotensin II is a powerful vasoconstrictor and increases blood pressure through a variety of mechanisms. Due to reduced angiotensin production, plasma concentrations of aldosterone are also reduced, resulting in increased excretion of sodium in the urine and increased concentrations of potassium in the blood.

Quinapril is indicated for the treatment of high blood pressure (hypertension) and as adjunctive therapy in the management of heart failure. It may be used for the treatment of hypertension by itself or in combination with thiazide diuretics, and with diuretics and digoxin for heart failure.

PHYSICAL AND CHEMICAL PROPERTIES

Molecular Formula:

C25H30N2O5.HCl

Molecular Weight:

474.98

CAS No.:

85441-61-8

Stability:

3 years	-20°C	Powder
6 months	-80°C	in solvent

Molecular Structure:

ANALYTICAL DATA

HPLC: 99.07% purity
NMR: Consistent with structure

Packaging & Shipping

Packaging :- 25 kg Fiber drum or as per Customer requirement

Details

product Name	Quinapril
Synonyms	Accupril; Asig
Molecular Formula	C₂₅H₃₀N₂O₅
Molecular Weight	438.52
InChI	InChI=1/C25H30N2O5/c1-3-32-25(31)21(14-13-18-9-5-4-6-10-18)26-17(2)23(28)27-16-20-12-8-7-11-19(20)15-22(27)24(29)30/h4-12,17,21-22,26H,3,13-16H2,1-2H3,(H,29,30)/t17-,21-,22-/m0/s1
CAS Registry Number	85441-61-8
Molecular Structure
Melting point	120-130℃
Hazard Symbols
Risk Codes
Safety Description	S22:; S24/25:;